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Numerical investigation on mixing intensification of ferrofluid and deionized water inside a microchannel using magnetic actuation generated by embedded microcoils for lab-on-chip systems

Saadat, M ; Sharif University of Technology | 2020

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  1. Type of Document: Article
  2. DOI: 10.1016/j.cep.2019.107727
  3. Publisher: Elsevier B.V , 2020
  4. Abstract:
  5. Effective and rapid mixing is crucial for chemical and biological processes. The purpose of the current study is to investigate the effect of steady and varying magnetic field on the mixing of a water-based ferrofluid and two streams of deionized water inside a microchannel for Lab-on-Chip applications. To this end, the nonlinear governing equations, the momentum equation, the continuity equation, the mass transport equation and the Maxwell-Ampere equations are numerically solved. A commercial code based on the finite-element method is used and the numerical simulations are validated by the experimental results in the literature. To augment the mixing performance, the effects of influencing parameters such as the magnetic field strength and frequency, inlet velocity, relative inlet velocity, and duty cycle (the ratio of signal activation on the total signal length) are investigated. A mixing efficiency as high as 94.4% only after 13 s is achieved with a peak current of 1 A, a frequency of 5 Hz, 100 μm/s of inlet velocity, a relative inlet velocity between the ferrofluid and water streams of 0.8 and a duty cycle of 0.2. This proposed model provides a versatile and low-cost solution to intensify microfluidic mixing performance and develop efficient Lab-on-Chip platforms. © 2019 Elsevier B.V
  6. Keywords:
  7. Ferrofluid ; Lab-on-chip ; Microfluidics ; Micromixing ; Deionized water ; Embedded systems ; Inlet flow ; Laboratories ; Magnetic field effects ; Magnetic fluids ; Magnetism ; Maxwell equations ; Microchannels ; Numerical methods ; Velocity ; Chemical and biologicals ; Influencing parameters ; Lab on chip ; Magnetic field strengths ; Mass transport equation ; Maxwell-Ampere equation ; Micro-mixing ; Numerical investigations ; Nonlinear equations
  8. Source: Chemical Engineering and Processing - Process Intensification ; Volume 147 , 2020
  9. URL: https://www.sciencedirect.com/science/article/abs/pii/S0255270119309043