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A versatile one-pot synthesis of 2,3,5-tri-substituted thiophenes from thiomorpholides

Matloubi Moghaddam, F ; Sharif University of Technology | 2003

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  1. Type of Document: Article
  2. DOI: 10.1016/S0040-4039(03)01548-X
  3. Publisher: Elsevier Ltd , 2003
  4. Abstract:
  5. An efficient method for the preparation of 2,3,5-trisubstituted thiophenes in a one-pot synthesis from thiomorpholides via the thio-Claisen rearrangement was developed. © 2003 Elsevier Ltd. All rights reserved
  6. Keywords:
  7. Thiomorpholine derivative ; Thiophene derivative ; Chemical structure ; Synthesis ; Proton nuclear magnetic resonance ; Column chromatography ; Claisen rearrangement
  8. Source: Tetrahedron Letters ; Volume 44, Issue 33 , 2003 , Pages 6253-6255 ; 00404039 (ISSN)
  9. URL: https://www.sciencedirect.com/science/article/abs/pii/S004040390301548X