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  1. KF/Al2O3 mediated aza-Michael addition of indoles to electron-deficient olefins
KF/Al2O3 mediated aza-Michael addition of indoles to electron-deficient olefins
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KF/Al2O3 mediated aza-Michael addition of indoles to electron-deficient olefins

Moghaddam, F. M

KF/Al2O3 mediated aza-Michael addition of indoles to electron-deficient olefins

Moghaddam, F. M ; Sharif University of Technology | 2006

574 Viewed
  1. Type of Document: Article
  2. DOI: 10.2174/157017806775224224
  3. Publisher: 2006
  4. Abstract:
  5. KF/Al2O3 efficiently catalyzes aza-Michael addition of indole and 3-methylindole to a variety of electron-deficient conjugated alkenes such as α,β-unsaturated ketones, amides and nitriles. The N-alkylation adducts are produced in good to excellent yields and relatively in short times. The catalyst can be recycled for subsequent reactions without any appreciable loss of efficiency. © 2006 Bentham Science Publishers Ltd
  6. Keywords:
  7. Electron-deficient olefins ; aza-Michael addition ; Indole ; N-alkylation ; KF/Al2O3
  8. Source: Letters in Organic Chemistry ; Volume 3, Issue 2 , 2006 , Pages 157-160 ; 15701786 (ISSN)
  9. URL: https://www.eurekaselect.com/76768/article/kfal2o3-mediated-aza-michael-addition-indoles-electron-deficient-olefins