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  1. Effects of Sr and Mg dopants on biological and mechanical properties of SiO2–CaO–P2O5 bioactive glass
Effects of Sr and Mg dopants on biological and mechanical properties of SiO2–CaO–P2O5 bioactive glass
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Effects of Sr and Mg dopants on biological and mechanical properties of SiO2–CaO–P2O5 bioactive glass

Sharifianjazi, F

Effects of Sr and Mg dopants on biological and mechanical properties of SiO2–CaO–P2O5 bioactive glass

Sharifianjazi, F ; Sharif University of Technology | 2020

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  1. Type of Document: Article
  2. DOI: 10.1016/j.ceramint.2020.06.030
  3. Publisher: Elsevier Ltd , 2020
  4. Abstract:
  5. In the present study, the effects of Sr and Mg were investigated on mechanical and biological properties of 58S bioactive glass (BG). SiO2-P2O5-CaO BG with different contents of Sr and Mg were synthesized via the sol-gel method and immersed in simulated body fluid (SBF) for several days to explore their biocompatibility. Precise analyses of the BG using X-ray powder diffraction, scanning electron microscopy, and transmission electron microscopy showed that the Mg-doped BG containing 8 wt % MgO possessed better biocompatibility. It was also found that mechanical properties of the BG could be improved by increasing the amounts of MgO and SrO. Both 5Sr-BG and 8Mg-BG samples did not exhibit any cytotoxicity while showing high alkaline phosphatase activity in comparison with control specimens. However, the Sr-doped BG sample including 5 wt % SrO demonstrated enhanced bioactivity and biocompatibility. © 2020 Elsevier Ltd and Techna Group S.r.l
  6. Keywords:
  7. Bioactivity ; Magnesium ; Strontium ; Bioactive glass ; Biocompatibility ; Body fluids ; Calcium oxide ; High resolution transmission electron microscopy ; Magnesia ; Mechanical properties ; Oxide minerals ; Phosphatases ; Scanning electron microscopy ; Silica ; Sol-gel process ; Sol-gels ; X ray powder diffraction ; 58S bioactive glass ; Alkaline phosphatase activity ; Biological properties ; Mg dopants ; Mg-doping ; Precise analysis ; Simulated body fluids ; Sr doped ; Strontium compounds
  8. Source: Ceramics International ; Volume 46, Issue 14 , 2020 , Pages 22674-22682
  9. URL: https://www.sciencedirect.com/science/article/pii/S027288422031676X