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    Pulse Electrodeposition of Chromium Coating From Trivalent Bath and Studying it’s Properties

    , M.Sc. Thesis Sharif University of Technology Araban, Vahid (Author) ; Ghorbani, Mohammad (Supervisor) ; Dolati, Abolghasem (Supervisor)
    Abstract
    Trivalent chromium plating has been known as a very promising technology to replace hexavalent chromium which is so toxic. The coatings obtained from tivalent chromium baths have lower thickness and Hardness and higher corrosion rate in comparison with deposits obtained from hexavalent chromium baths.A few studies on pulse plating of trivalent chromium as an effective way to enhance the coating properties have been published.
    In this research glycine was chosen as complexing agent.The results have shown that in pulse plating at 1 Hz, Duty cycle 50%, peak current density 0/2 A/Cm2 and after 30 minutes, thickness achieves 13 µm which is much greater in comparison with coatings obtained in... 

    Application of Cellulose Nanofibers Coated Quartz Crystal Microbalance (QCM) Biosensor for Amino Acid Detection in Aqueous Media

    , Ph.D. Dissertation Sharif University of Technology Hosseini, Marzieh Sadat (Author) ; Irajizad, Azam (Supervisor) ; Vossoughi, Manouchehr (Supervisor)
    Abstract
    Developing a simple, cost effective and accurate detection method for L-lysine (Lys), L-leucine (Leu) and glycine (Gly) as the important analytes in clinical diagnostics, biological processes and food industries is of great interest. Therefore, in the first part of this research, cellulose nanofibrils (CNFs) were coated on a quartz crystal microbalance (QCM) surface by spin coating to achieve a QCM biodetector for Gly. Thus, the two-layer CNFs coating was selected as sensing film and was applied for following experiments. In the next step, the coated QCMs were carefully characterized before and after interaction with Gly using water contact angle (WCA), Fourier transform infrared... 

    Application of Cellulose Nanofibers Coated Quartz Crystal Microbalance (QCM)Biosensor for Amino Acid Detection in Aqueous Media

    , Ph.D. Dissertation Sharif University of Technology Hosseini, Marzieh Sadat (Author) ; Iraji Zad, Azam (Supervisor) ; Vossoughi, Manouchehr (Supervisor)
    Abstract
    Developing a simple, cost effective and accurate detection method for L-lysine (Lys), L-leucine (Leu) and glycine (Gly) as the important analytes in clinical diagnostics, biological processes and food industries is of great interest. Therefore, in the first part of this research, cellulose nanofibrils (CNFs) were coated on a quartz crystal microbalance (QCM) surface by spin coating to achieve a QCM biodetector for Gly. Thus, the two-layer CNFs coating was selected as sensing film and was applied for following experiments. In the next step, the coated QCMs were carefully characterized before and after interaction with Gly using water contact angle (WCA), Fourier transform infrared... 

    Synthesis of pH-Sensitive, Folate-Functionalized Silica-Glycine@Liposome Core-Shell System for Doxorubicin Controlled Release: In Vitro Studies

    , Ph.D. Dissertation Sharif University of Technology Gooneh Farahani, Sahar (Author) ; Simchi, Abdolreza (Supervisor) ; Imani, Mohammad (Supervisor)
    Abstract
    In the design of many drug delivery systems, the primary goal is to achieve controlled release at predetermined rates over a duration appropriate for the therapeutic application. Maintaining the drug concentration within the optimal therapeutic window reduces adverse side effects, lowers the required drug dose, optimizes drug utilization, and enhances patient compliance. An effective strategy for targeted drug delivery is the design of systems capable of providing the required amount of drug at the desired time and site in the body with controlled release. In this study, a silica-liposome hybrid carrier was designed and synthesized to achieve pH-responsive controlled release. Liposomes are...