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    Entanglement Hamiltonian of Interacting Systems and its Applications in the Study of Strongly Correlated Systems

    , M.Sc. Thesis Sharif University of Technology Najafzadeh Oskoui, Hanieh (Author) ; Vaezi, Mir Abolhassan (Supervisor)
    Abstract
    Recent advances in numerical computations in the field of strongly correlated systems have provided us to calculate the entanglement spectrum and the entanglement entropy for interacting systems. Calculating the explicit form of the entanglement Hamiltonian (a.k.a. the modular Hamiltonian) is considered as a difficult problem.In this dissertation, we intend to introduce a method and by means of the d ensity-matrix-renormalization-group algorithm to obtain for the first time the second quantization form of the entanglement Hamiltonian of interacting systems at zero temperature. We implement our method for one-dimensional Heisenberg spin chain and also Heisenberg model on a square lattice... 

    Design and Control of Parallel Hybride Electric Samand Vehicle

    , M.Sc. Thesis Sharif University of Technology Parvini Oskoui, Yasha (Author) ; Vossoughi, Gholamreza (Supervisor)
    Abstract
    The final target of this research is to design an appropriate intelligent control strategy for energy management purposes in a well designed parallel hybrid electric vehicle. In the first step, the conventional “Samand” vehicle has been simulated using real data for vehicle parameters and power train components, has been simulated. Using experimental results, simulation results are validated. In the second step due to the primarily defined parallel electric assist control strategy (PEACS) for the hybrid electric vehicle and performance requirements, components such as engine, electric machine and battery pack were selected and sized. In the final step a Fuzzy Logic Controller (FLC) has been... 

    Lithography-directed Self-assembly for Designing Drug Particles of Various Sizes and Morphologies

    , M.Sc. Thesis Sharif University of Technology Forghan Tarigheh, Fatemeh (Author) ; Safari, Hanieh (Supervisor)
    Abstract
    To design a drug delivery system, the drug must be encapsulated within a carrier matrix. One of the main challenges in this field is encapsulating high drug doses while achieving a linear release profile at the target site to maintain drug concentration for optimal therapeutic effects. Consequently, many research groups have focused on refining fabrication techniques to maximize loading efficiency and optimize drug release profiles from delivery systems. A potential approach to addressing this issue is the direct fabrication of a controlled-release system from the active pharmaceutical ingredient (API) itself, eliminating the need for a carrier matrix. Studies have demonstrated that such... 

    3D Multi Target Tracking

    , M.Sc. Thesis Sharif University of Technology Najafzadeh, Nima (Author) ; Kasaei, Shohreh (Supervisor)
    Abstract
    The purpose of multi target tracking, is tracking multiple target in each frame of video sequences simultaneously. Object tracking encounters many challenges. Two major challenges of tracking problem that we focus on in them in this thesis are detecting object in each frame of video sequence and handling occlusion problem. Our proposed method for multi target tracking considers one target as a main target and other targets as subsidiary targets. Proposed method track objects in initial view by Kalman filter that is adapted and tuned for multi target tracking. In case of occlusion our method uses data from auxiliary view for handling occlusion. In auxiliary view objects that are occluded in... 

    Multiple soccer players tracking

    , Article Proceedings of the International Symposium on Artificial Intelligence and Signal Processing, AISP 2015, 3 March 2015 through 5 March 2015 ; March , 2015 , Pages 310-315 ; 9781479988174 (ISBN) Najafzadeh, N ; Fotouhi, M ; Kasaei, S ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2015
    Abstract
    This paper, describes a solution for tracking multiple soccer players, simultaneously, in soccer ground. It adapts Kalman filter for tracking multiple players. Adapting Kalman filter is divided to four main tasks. The first task is defining the state vector for multiple object tracking. The second task is determining a motion model for estimating the position of soccer players in the next frame. The third task is defining an observation method for detecting soccer players in each frame. Finally, the fourth task is tuning the measurement noise covariance and estimating noise covariance. In the third task, a novel observation method for detecting soccer players is proposed. This method divides... 

    Using game theory to battle jammer in control channels of cognitive radio ad hoc networks

    , Article 2016 IEEE International Conference on Communications, ICC 2016, 22 May 2016 through 27 May 2016 ; 2016 ; 9781479966646 (ISBN) Oskoui, M. G ; Khorramshahi, P ; Salehi, J. A ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2016
    Abstract
    Because of opportunistic spectrum access, cognitive radio networks is a promising solution for spectrum scarcity problem. In cognitive radio networks, users need to communicate through control channels in order to cooperate for sharing sensing information, channel sharing and spectrum management. As a result control channels security is of a great importance. If control channels get jammed, network's performance degrades dramatically; therefore, the jammers primary target in cognitive radio networks is to demolish control channels in order to disturb the network's performance. Traditionally hopping sequences were used to battle this problem but considering cognitive radio networks... 

    Using Game Theory to Battle Jammer in Control Channel of Ad-hoc Cognitive Radio Networks

    , M.Sc. Thesis Sharif University of Technology Golzari Oskoui, Mohammad Reza (Author) ; Salehi, Javad (Supervisor)
    Abstract
    Due to both dynamic and opportunistic spectrum access, Cognitive radio networks is a promising solution for spectrum scarcity problem. In cognitive radio networks, users need to have a control channels in order to cooperate for sharing the sensing information, channel sharing and etc. In Ad-hoc cognitive radio networks because of the absence of infrastructure and central nodes, every user runs a distributed algorithm to create a common control channel. If the control channel gets jammed, network’s performance degrades dramatically, therefore the jammer’s target in cognitive radio networks is the control channels to disturb the networks’ performance. The traditional solution to confront... 

    Impact of the Shape of the Loaded Particles on the Mechanical Properties of the Scaffolds and their Interaction with Macrophages

    , M.Sc. Thesis Sharif University of Technology Tymuri, Fatemeh (Author) ; Mashayekhan, Shohreh (Supervisor) ; Safari, Hanieh (Supervisor)
    Abstract
    Osteoarthritis is a common musculoskeletal disorder and the most prevalent form of arthritis. To date, no comprehensive cure has been reported for osteoarthritis, and its clinical management remains challenging. The primary therapeutic goals in the early stages of osteoarthritis are to increase joint mobility and control disease progression by continuously releasing drugs and molecules modulating inflammatory responses and reducing pain. Smart drug delivery platforms are one of the strategies to overcome the challenges of injectable and oral medications. Additionally, drug carrier particles can have different therapeutic targets based on their size and shape. Different therapeutic... 

    Anti-aggregation of gold nanoparticles for metal ion discrimination: a promising strategy to design colorimetric sensor arrays

    , Article Sensors and Actuators, B: Chemical ; Volume 270 , 2018 , Pages 545-551 ; 09254005 (ISSN) Najafzadeh, F ; Ghasemi, F ; Hormozi Nezhad, M. R ; Sharif University of Technology
    2018
    Abstract
    The first report of anti-aggregation-based sensor arrays is presented. The strategy is based on the competitive interaction of citrate-capped gold nanoparticles (AuNPs) and heavy metal ions (i.e., Hg(II), Ag(I), Fe(III), and Pb(II)) with three aggregation reagents (i.e., cysteine, melamine, and arginine). In the presence of aggregation reagent, the color and UV–vis spectra of AuNPs are changed indicating the aggregation of AuNPs. Addition of the aggregation reagents which are firstly treated with the ions, causes AuNPs turn from the aggregation to the dispersion state. The anti-aggregation capability of ions towards various aggregation reagents is different because of distinct stability... 

    Design of an Optoelectronic Tongue Based on Anti-Aggregation of Gold Nanoparticles for Detection and Classification of Heavy Metal Ions

    , M.Sc. Thesis Sharif University of Technology Najafzadeh, Fatemeh (Author) ; Hormozi-Nezhad, Mohammad Reza (Supervisor)
    Abstract
    The first report of anti-aggregation-based sensor arrays is presented. The strategy is based on the competitive interaction of citrate-capped gold nanoparticles (AuNPs) and heavy metal ions (i.e., Hg(II), Ag(I), Fe(III), and Pb (II)) with three aggregation reagents (i.e., cysteine, melamine, and arginine). In the presence of aggregation reagent,the color and UV–vis spectra of AuNPs are changed indicating the aggregation ofAuNPs. Addition of the aggregation reagents which are firstly treated with the ions, causes AuNPs turn from the aggregation to the dispersion state. The anti-aggregation capability of ions towards various aggregation reagents is different because of distinct stability... 

    Explicit analytic solution for the nonlinear ion sound waves equation

    , Article Applied Mathematical Sciences ; Volume 4, Issue 21-24 , 2010 , Pages 1183-1195 ; 1312885X (ISSN) Doosthoseini, A ; Sharifi, A ; Jafari, A. J ; Oskoui, R. N ; Sharif University of Technology
    2010
    Abstract
    In this article, we use an efficient analytical method called homotopy analysis method (HAM) to derive an approximate solution of nonlinear ion sound waves equation. Actually, we solved Korteweg-de Vries equation arises in a one-dimensional macroscopic plasma model describing the weakly nonlinear evolution of ion sound speed by the HAM. Unlike the perturbation method, the HAM does not require the addition of a small physically parameter to the differential equation. It is applica-ble to strongly and weakly nonlinear problems. Moreover, the HAM involves an auxiliary parameter, which renders the convergence param-eter of series solutions controllable, and increases the convergence, and... 

    Pinch Analysis of Heat Exchanger Networks in the Crude Oil Distillation Unit of Bandar-Abbas Refinery

    , M.Sc. Thesis Sharif University of Technology Hesabi, Ashkan (Author) ; Sadrhosseini, Hanieh (Supervisor) ; Shafii, Mohammad Behshad (Supervisor)
    Abstract
    Since oil prices continue to increase, energy conservation remains the prime industrial concern. Existing processes in power plants and oil refineries are not energy efficient as they should be therefore new projects can be defined to increase the energy efficiency without incurring any cost. The most appropriate utility for the processes should be explored to reduce emissions, increase the plant capacities and improve product qualities and energy efficiencies by one coherent strategic plan for the overall site which can be achieved by a full understanding of pinch technology and awareness of the available tools for applying it in practical way. Since the distillation unit of crude oil... 

    The Optimization of Self-Assembled Coacervate Drug Delivery Systems to Enhance Uptake by Macrophages and Their Polarization Towards an Anti-Inflammatory Phenotype

    , M.Sc. Thesis Sharif University of Technology Delzendeh Rooy, Alireza (Author) ; Safari, Hanieh (Supervisor) ; Mashayekhan, Shohreh (Supervisor)
    Abstract
    Macrophages play a crucial role in the healing process of chronic wounds in diabetic patients. These cells polarize from a pro-inflammatory M1 phenotype to an anti-inflammatory M2 phenotype, guiding the initial inflammation toward tissue repair and regeneration. In diabetic patients, physiological disturbances impair this polarization, resulting in persistent, chronic, and inflamed wounds. Glucocorticoid anti-inflammatory drugs are commonly used but have serious side effects, necessitating targeted delivery systems. This study aims to design and optimize self-assembled complex coacervate drug delivery system composed of gelatin and sodium alginate (GA/SA CCA) that can selectively uptake by... 

    A Study of Laboratory Proposals for Detecting Gravitational Entanglement in Quantum Interferometry

    , M.Sc. Thesis Sharif University of Technology Najafzadeh, Ayda (Author) ; Khosravi, Nima (Supervisor) ; Karimipour, Vahid (Supervisor)
    Abstract
    In recent years, growing attention has been directed toward the possibility of testing the quantum nature of gravity using laboratory-scale systems; a pursuit motivated by the fundamental question of whether the gravitational field, like the other fundamental interactions, possesses quantum degrees of freedom or can be fully described by a classical theory. In this thesis, we begin by reviewing the principles of quantum interference and the role of path-dependent phase in experiments such as atomic interferometry and the gravitational Aharonov–Bohm effect, illustrating how these techniques enable the detection of extremely weak gravitational influences. We then introduce quantum entanglement... 

    Synthesis of Graphene Quantum Dots for Biomedical Application

    , M.Sc. Thesis Sharif University of Technology TaghaviLarijani, Hanieh Sadat (Author) ; Sadrnezhaad, KHatiboleslam (Supervisor) ; Ahhadiaan, Mohammad Mehdi (Co-Advisor)
    Abstract
    Graphene quantum dots (GQDs) as a sort of carbon-based nanomaterials are applied in a multitude of exciting areas. They are effective fluorescent probe for many potential biological and medical applications. In comparison to conventional organic fluorescent probes (organic dyes), GQDs have substantial advantages, such as photostability, excellent solubility, low cytotoxicity and biocompatibility.
    In this thesis, green fluorescent GQDs have been prepared via solvothermal method from graphite powder.Various analysis methods were utilized to characterization of the product. So, several experiments on GQDs in solution and in solid substrate at room temperature have been performed. The... 

    Benchmarking of Monte Carlo model of Siemens Oncor® linear accelerator for 18MV photon beam: determination of initial electron beam parameters

    , Article Journal of X-Ray Science and Technology ; Volume 27, Issue 6 , 2 January , 2020 , Pages 1047-1070 Najafzadeh, M ; Hoseini Ghafarokhi, M ; Bolagh, R. S. M ; Haghparast, M ; Zarifi, S ; Nickfarjam, A ; Farhood, B ; Chow, J. C. L ; Sharif University of Technology
    IOS Press  2020
    Abstract
    OBJECTIVE: This study aims to benchmark a Monte Carlo (MC) model of the 18 MV photon beam produced by the Siemens Oncor® linac using the BEAMnrc and DOSXYZnrc codes. METHODS: By matching the percentage depth doses and beam profiles calculated by MC simulations with measurements, the initial electron beam parameters including electron energy, full width at half maximum (spatial FWHM), and mean angular spread were derived for the 10×10 cm2 and 20×20 cm2 field sizes. The MC model of the 18 MV photon beam was then validated against the measurements for different field sizes (5×5, 30×30 and 40×40 cm2) by gamma index analysis. RESULTS: The optimum values for electron energy, spatial FWHM and mean... 

    Diabetes-associated thigh muscle degeneration mediates knee osteoarthritis–related outcomes: results from a longitudinal cohort study

    , Article European Radiology ; Volume 33, Issue 1 , 2023 , Pages 595-605 ; 09387994 (ISSN) Mohajer, B ; Moradi, K ; Guermazi, A ; Dolatshahi, M ; Zikria, B ; Najafzadeh, N ; Kalyani, R. R ; Roemer, F. W ; Berenbaum, F ; Demehri, S ; Sharif University of Technology
    Springer Science and Business Media Deutschland GmbH  2023
    Abstract
    Objectives: We examined the association between diabetes mellitus (DM) and longitudinal MRI biomarkers for thigh muscle degeneration in patients with knee osteoarthritis (KOA) and their mediatory role in worsening KOA-related symptoms. Methods: The Osteoarthritis Initiative (OAI) participants with radiographic KOA (Kellgren-Lawrence grade ≥ 2) were included. Thighs and corresponding knees of KOA patients with versus without self-reported DM were matched for potential confounders using propensity score (PS) matching. We developed and used a validated deep learning method for longitudinal thigh segmentation. We assessed the association of DM with 4-year longitudinal muscle degeneration in... 

    Role of Thigh Muscle Changes in Knee Osteoarthritis Outcomes: Osteoarthritis Initiative Data

    , Article Radiology ; Volume 305, Issue 1 , 2022 , Pages 169-178 ; 00338419 (ISSN) Mohajer, B ; Dolatshahi, M ; Moradi, K ; Najafzadeh, N ; Eng, J ; Zikria, B ; Wan, M ; Cao, X ; Roemer, F. W ; Guermazi, A ; Demehri, S ; Sharif University of Technology
    Radiological Society of North America Inc  2022
    Abstract
    Background: Longitudinal data on the association of quantitative thigh muscle MRI markers with knee osteoarthritis (KOA) outcomes are scarce. These associations are of clinical importance, with potential use for thigh muscle–directed disease-modifying interventions. Purpose: To measure KOA-associated longitudinal changes in MRI-derived muscle cross-sectional area (CSA) and adipose tissue and their association with downstream symptom worsening and knee replacement (KR). Materials and Methods: In a secondary analysis of the Osteoarthritis Initiative multicenter prospective cohort (February 2004 through October 2015), knees of participants with available good-quality thigh MRI scans at baseline...