Sharif Digital Repository

Modern techniques for expanding stem cells play a substantial role in tissue engineering: the raw material that facilitates regeneration of damaged tissues and treats diseases. The environmental conditions and bioprocessing methods are the primary determinants of the rate of cultured stem cell proliferation. Bioceramic scaffolds made of calcium phosphate are effective substrates for optimal cell proliferation. The present study investigates the effects of two bioceramic scaffolds on proliferating cells in culture media. One scaffold was made of hydroxyapatite and the other was a mixture of hydroxyapatite and ferromagnetic material (Fe3O4 nanoparticles). Disk-shaped (10 mm × 2 mm) samples of... 

In this study, the effect of hydrophobicity of environmentally responsive surface-modified silica nanoparticles on the stability and surface activity of the nanoparticles is examined. To this end, n-propyl, n-hexyl, or n-octyl chains and methoxy poly(ethylene glycol) chains at various quantities were coated covalently on the surface of silica nanoparticles to regulate the hydrophobicity of the responsive nanoparticles. Various experimental tools such as stability analysis, interfacial-tension and contact-angle measurements, and emulsion formation were performed to investigate the effect of hydrophobicity. It became evident that the presence of the hydrophobic agents influences considerably... 

In this article a comprehensive numerical study is performed to compare the effect of fluid flow across a duct with various cross sectional shapes and with different velocities of the flow. Circular, elliptical and rectangular cross sections have been chosen for the ducts and air flows across them with four values of low Reynolds numbers in the range of Re = 1 to Re = 1000. Continuity and momentum equations with proper boundary conditions are solved in two dimensions. Streamlines, pressure distribution and Velocity profiles are obtained and creation of vortices, boundary layers, separation region, wake region, reattachment point and stagnation points are studied in detail and the results are... 

Problems related to the three-dimensional (3D) dynamics of the deploying flexible arms subjected to base angular motions are studied with simulated tip payloads and actual deployment trajectories. To facilitate the solution, an equivalent dynamical system is developed by introducing the inertial reaction forces on the arm, while the equations of motion are derived in the non-Newtonian reference frame attached to the arm. The dynamic behavior of the arm is investigated both by the finite element and assumed Modes methods for the purpose of verification. This study reveals that base angular motions lead to considerable couplings between the two lateral displacements and axial motions.... 

The loads induced on the spacecraft orbiting the Earth by the deploying elastic arm are investigated. The coupled equations of motion of the arm with the vehicle orbital mechanics are used to describe the 3D dynamic behavior of the flexible-appendage and the related disturbing loads induced on the spacecraft. To this end, an equivalent dynamical system is derived for the arm by applying an attached Non-Newtonian Reference Frame which is subjected to the orbital motion and geocentric pointing maneuver of the spacecraft. With the help of the Assumed Modes Method, the behavior of the arm attached to the spacecraft in Keplerian orbits is studied. The results show that deploying the arm in some... 

Deployment inertial effects of a spacecraft appendage on its flexible dynamics are investigated. The Euler-Bernoulli beam theory and the actual deployment profile, in which appendage axial motion accelerates from static state and then decelerates to end at zero velocity and acceleration, are employed. The study is concentrated on the arm dynamic stiffness introduced by inertial effects of the arm deployment, and the resultant effects on the arm flexible motions. Lagrange's equations and some appropriate shape functions in the series approximation method are employed to study the arm lateral elastic displacements. Finally a system of ordinary differential equations with time varying... 

The dynamics of the flexible robot arm subjected to tip mass during an actual deployment is studied. The Euler-Bernoulli beam theory and the real deployment are considered in the simulation. A new real axial velocity profile is developed. This new suggested profile simulates the actual deployment such that the arm movement starts from immovability and after attaining the final required length comes back again to the static state. Using Lagrange's equation, the equations of motion of the system are derived to study the system dynamics in this suggested deployment profile. A series approximation is used to represent the lateral elastic displacements. Using variables separation and also some... 

Shot peening (SP), as one of the severe plastic deformation (SPD) methods is employed for surface modification of the engineering components by improving the metallurgical and mechanical properties. Furthermore, artificial neural network (ANN) has been widely used in different science and engineering problems for predicting and optimizing in the last decade. In the present study, effects of conventional shot peening (CSP) and severe shot peening (SSP) on properties of AISI 1060 high carbon steel were modelled and compared via ANN. In order to networks training, the back propagation (BP) error algorithm is developed and data of experimental tests results are employed. Experimental data... 

Single-phase polycrystalline NdBa2-xPrxCu 3O7+δ (0 ≤ x ≤ 0.5) have been prepared by the standard solid-state reaction. The results of X-ray diffraction measurements confirm the formation of 123 single phase. A superconductor-insulator transition at XcSIT = 0.3 has been observed for the samples. The magnetoresistance of the samples have been investigated within the thermally activated flux creep model. The pinning energy decreases with the magnetic field application and Pr-doping. A scaling relation as power law dependence of pinning energy to the magnetic field has been obtained. The derived pinning energy shows that the Pr-doping plays the role of weak link. The normal state resistivity... 

The size mono-dispersity, saturation magnetization, and surface chemistry of magnetic nanoparticles (NPs) are recognized as critical factors for efficient biomedical applications. Here, we performed modified water-in-oil inverse nano-emulsion procedure for preparation of stable colloidal superparamagnetic iron oxide NPs (SPIONs) with high saturation magnetization. To achieve mono-dispersed SPIONs, optimization process was probed on several important factors including molar ratio of iron salts [Fe3+ and Fe2+], the  

A thorough investigation of the dynamics of finite-mass satellites with a deployable elastic arm is presented. This work is focused on the interaction between spacecraft rigid body motion and its flexible arm dynamics during the deployment process. The classical Newton–Euler formulation and the Lagrangian approach are applied to the study of the dynamics of spacecraft and its deploying arm. Utilizing a non-Newtonian floating frame to define the arm elastic deformation field, the interactions between the spacecraft and its moving arm have been simulated. Complete equations of motion show that the spacecraft motion induces dynamical stiffness on the arm; in addition, axial and lateral motions... 

A thorough investigation of the dynamics of finite-mass satellites with a deployable elastic arm is presented. This work is focused on the interaction between spacecraft rigid body motion and its flexible arm dynamics during the deployment process. The classical Newton–Euler formulation and the Lagrangian approach are applied to the study of the dynamics of spacecraft and its deploying arm. Utilizing a non-Newtonian floating frame to define the arm elastic deformation field, the interactions between the spacecraft and its moving arm have been simulated. Complete equations of motion show that the spacecraft motion induces dynamical stiffness on the arm; in addition, axial and lateral motions... 

Mechanical failures in most cases originate from the exterior layers of the components. It is considerably effective to apply methods and treatments capable to improve the mechanical properties on component’s surface. Surface nanocrystallization produced by severe plastic deformation (SPD) processes such as severe shot peening (SSP) is increasingly considered in the recent years. However, artificial intelligence systems such as artificial neural network (ANN) as an efficient approach instead of costly and time consuming experiments is widely employed to predict and optimize the science and engineering problems in the last decade. In the present study the application of ANN in predicting of... 

The experimental observations indicate that the mechanical behavior of micro and nano scale structures is size-dependent. In this study, employing the modified couple stress theory the size-dependent strain energy release rate of notched Euler-Bernoulli beams made of functionally graded material (FGM) is formulated. The normalized energy release rate for the problem of three-point bending in notched FG beams is obtained using the procedure established by Kienzler and Herrmann [Kienzler R, Herrmann G, An elementary theory of defective beams. Acta Mech 1986; 62:37-46]. It is assumed that the material properties vary continuously along the beam thickness according to a power law distribution.... 

In endurance time method, seismic performance of structures under artificial intensifying accelerograms is investigated. In this method, the time duration of excitation (target time) will be assigned on the basis of linear response spectra. Damage spectra, which are the variation of a damage index versus the system period, can be used effectively to modify the target time of the excitations. In this research, various damage indices for a number of steel moment frames are estimated using the endurance time method with two types of target time, and the results are compared with those corresponding to the scaled real earthquakes. It is observed that damage estimation of the frames via the... 

In seismic resistant design of moment frames, the structure behavior under earthquakes has to be examined considering various damage criteria. Damage indices can be estimated by Endurance Time (ET) method with minimum computational effort. The quality of this estimation can be improved in different ways. In this paper, the graphs of a certain damage index versus natural period of the structure, called damage spectra, are produced applying intensifying ET records and scaled Ground Motions (GM). Then, the excitation duration of ET acceleration functions (target time) is modified in order to reach acceptable consistency between ET and GM damage spectra. Moreover, various damage indices of a... 

In endurance time method, seismic performance of structures under artificial intensifying accelerograms is investigated. In this method, the time duration of excitation (target time) will be assigned on the basis of linear response spectra. Damage spectra, which are the variation of a damage index versus the system period, can be used effectively to modify the target time of the excitations. In this research, various damage indices for a number of steel moment frames are estimated using the endurance time method with two types of target time, and the results are compared with those corresponding to the scaled real earthquakes. It is observed that damage estimation of the frames via the...