Sharif Digital Repository

Parkinson's disease is a destructive and long-term disease of the central nervous system. This disease especially affects the motor system. Parkinson's patients can be studied under dopaminergic and non-dopaminergic conditions. The non-dopaminergic state means not taking the drug, for at least 12 hours, and the dopaminergic state, from one hour to less than 12 hours after taking the usual dose of the dopaminergic drug. The aim of this study is to examine and compare the statistics and characteristics of Parkinson's patients in dopaminergic and non-dopaminergic states, focusing on reaching and tracking activities. It also aims to analyze the differences before and after rehabilitation in... 

An optimal-fuzzy low altitude two phase CLOS guidance algorithm for a vertically launched flying vehicle is presented. In addition, the required relations for determining the proper rotation angle of interceptor in the launch phase are derived. The guidance algorithm is designed for a three point guidance system and utilizes fuzzy sliding mode control as a regulator to compensate the guidance loop errors. Furthermore, for the purpose of trajectory shaping, a fuzzy system was employed to calculate the augmented elevation angle. Finally, a multi-objective optimization algorithm is used to determine 20 unknown parameters of the guidance law and 11 parameters of trajectory shaping system.... 

Quantum correlations are among most intriguing problems in physics. Bell’s inequality which was proved in 1964 provides with us the possibility of comparing the predictions of quantum theory with what an underlying local realistic theory may reproduce for some given observables in correlated states. The violation of Bell’s inequality in practice prohibits the existance of such underlying theories. Yet, it is not clear which of the assumption, i.e., locality or reality is responsible for explaining the experimentally verified violations. In 2003, a Nobel prizewinner A. J. Leggett proved a new inequality in which the locality assumption was not crucial. Here, we explore different aspects of... 

Graph Labeling is one of the most active initiatives in graph theory which was introduced in the early 1960’s. One of the most prominent kind of labeling in literature is magic-type labeling inspired by defining magic numbers and magic squares. It also encompasses various types. Total edge magic labeling of Graph G, is a bijection f from V(G)∪E(G) on the set of {1,2,…,|V(G) |+|E(G) |}, on this condition that the summation of each edge label and its vertices’ labels is constant for all edges. Since introducing total edge magic labeling, numerous researches is done that mostly are dedicated to prove mathematical theorems and depicting a whether a distinct graph is magic or not. Therefore, it... 

Using free laccase, enzymatic decolorization of two azo dyes were optimized. The optimum conditions with the aim of maximizing the decolorization of AB92 dye (92.30%) were: dye concentration = 11.85 mg L-1, pH = 5.1, and enzyme concentration = 98.37 mg L-1. While, these conditions to achieve the maximum decolorization yield of DR23 (95.60%) were: dye concentration = 17.68 mg L-1, pH 3.7 and enzyme concentration =97.89 mg L-1.In the second part, the laccase enzyme was covalently immobilized onto GO nanosheets. At the concentration of graphene oxide and laccase enzyme equal to 1 mg mL-1 and 0.9 mg mL-1, respectively, the enzyme loading was 156.5 mg g-1 and the immobilization efficiency was... 

In this research, the design of control system has been studied for a special flying vehicle at whole of flight time. This flying vehicle is vertically launched and few time after launch its attitude changes to the desired attitude by a reaction jet control system, then the acceleration commands are tracked when the aerodynamic is activated. Design process includes attitude control system design in launch phase and aerodynamic control system design. Because of the existence of nonlinear and multi-variable dynamics in the flying vehicle and the presence of uncertainty and disturbance, combination of nonlinear, robust and adaptive methods are used in controller design process. Design of... 

Regarding decreasing resources of fossil fuels and their increasing costs in addition to their environmental pollutions, today, producing bio fuels from wastes such as lignocellulosic materials is of great interest. A fundamental stage in conversion of lignocellulosic materials into bio fuels, such as bio ethanol, is the enzymatic hydrolysis of these materials to produce reducing sugars. Researches have shown high costs of this stage. Optimization of enzymatic hydrolysisconditions is a major step in economization of this process.In this work corn hull is used to produce glucose. Corn hull is a kind of lignocellulosic material that due to high carbohydrate content is used as substrate. Our... 

The concurrent flow of oil and water is a common occurrence in the field of multiphase flow in different fields including petroleum industry. In oil and gas, production engineers often face a situation in which more than one phase is flowing through the producers. In such conditions an accurate assessment of pressure loss inside the well plays a vital role in efficient and effective production planning. Changes in well orientation, wellbore diameter, reservoir and fluid properties as well as fluid flow rates are among parameters in which will affect the flow patterns that can occur inside a well during its life time. These flow patterns are created as a result of a competition between... 

Casing design is one of the most expensive parts in the drilling of oil wells, and any cost reduction with the basic design of these casing strings will significantly reduce the total cost of the operation. In recent years, occurring scenarios-based casing design has become popular; Because in many cases, it eliminates non-occurring scenarios such as gas kick and saves on drilling costs. In this study, we have tried to investigate all scenarios that may occur during the lifetime of the well, whether drilling or production, and for each well, based on its own field information, possible scenarios for each casing part are selected separately and the applying loads are calculated. For this... 

The electrochemical oxidation behavior of the anti-inflammatory drug piroxicam was investigated. A carbon nanoparticle (CNP)-chitosan (CS) film-coated graphite electrode (PGE) was fabricated and the electrochemical behaviors of piroxicam on its surface was investigated by the means of cyclic voltammetry (CV), linear sweep voltammetry (LSV) and electrochemical impedance spectroscopy (EIS). In comparison to the bare PGE, at the surface of the CNP-CS film modified electrode, the oxidation peak current of piroxicam increased significantly and the peak potential shifted negatively. Consequently, a simple and sensitive electroanalytical method was developed for the determination of piroxicam. The...