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    L-sorbose production by gluconobacter oxydans using submerged fermentation in a bench scale fermenter

    , Article Applied Food Biotechnology ; Volume 7, Issue 1 , 2020 , Pages 41-48 Alizad Derakhshi Azar, S ; Alemzadeh, I ; Sharif University of Technology
    National Nutrition and Food Technology Research Institute  2020
    Abstract
    Background and objective: L-Sorbose, as a precursor of ascorbic acid, can be biologically produced using Gluconobacter oxydans. The aim of this study was to optimize production of L-Sorbose by controlling concentration of the substrates and starter cultures. Material and methods: In this study, effects of three various fermentation parameters on the concentration of L-sorbose were assessed using fermenter (28°C, 1.4 vvm) and response surface methodology. These parameters included quantities of D-sorbitol (120-180 g lDw-1) (Deionized water) and yeast extract (6-18 g lDw-1) and inoculum/substrate ratios (5-10%). Results and conclusion: Results showed that the fitted model with high values of... 

    Investigation of biotechnological production of Vitamin C

    , M.Sc. Thesis Sharif University of Technology Alizad Derakhshi Azar, Sepideh (Author) ; Alemzadeh, Iran (Supervisor)
    Abstract
    Vitamin C is an essential for the survival of human, animals and plants. Human and most animals can not produce vitamin C in their bodies, thus the need to produce vitamin C as a supplement is necessary. Nowadays, for the industrial production of vitamin C, two Chinese and Rychstyn methods are used, the first method is a two-step method which is accomplished biological and the second method is done chemically. In Chinese method, first step, which is the most important step is production of L-sorbose from D-sorbitol by Gluconobacter oxydans bacteria .Thus, in this study it was attempted to optimize the production of L-sorbose to be used in industrial production of L-ascorbic acid. In... 

    Decentralized triangular relative localization of multiple UAVs based on relative range and inertial measurements

    , Article ISA Transactions ; Volume 149 , 2024 , Pages 217-228 ; 00190578 (ISSN) Alizad, M ; Nobahari, H ; Sharif University of Technology
    2024
    Abstract
    In this paper, a novel algorithm for cooperative relative localization of multiple Unmanned Aerial Vehicles (UAVs) is proposed based on relative range and inertial measurements. In this algorithm, a relative motion estimation model is established for each group of three UAVs that can form a triangle in space. Each group member estimates the relative position and heading angle of the other group members and shares the estimation results with the other group members. When members satisfy the triangle law among their estimated relative position vectors, they can estimate more accurately. After analyzing the observability of the presented model, the necessary conditions for observability are... 

    Design of a Bi-objective Integrated Production-distribution Network with Stochastic Demand

    , M.Sc. Thesis Sharif University of Technology Derakhshi, Mohammad (Author) ; Akhavan Niaki, Taghi (Supervisor)
    Abstract
    Supply chain has gained great interest from researchers in recent years. In this regard, proposing efficient and practical models that reflect different supply chain aspects is challenging. This research deals with an integrated production-distribution supply chain model which incorporates few parties along with some processes to obtain raw materials from raw material suppliers and to convert them to semi and final products and then distribute them indirectly using warehouses to end users. To tackle the problem, we propose a mixed integer linear programming model. Due to the combinatorial nature of the problem, a metaheuristic algorithm is designed to solve industrial size problems.... 

    Seizure Detection in Generalized and Focal Seizure from EEG Signals

    , M.Sc. Thesis Sharif University of Technology Mozafari, Mohsen (Author) ; Hajipour, Sepideh (Supervisor)
    Abstract
    Epilepsy is one of the diseases that affects the quality of life of epileptic patients. Epileptic patients lose control during epileptic seizures and are more likely to face problems. Designing and creating a seizure detection system can reduce casualties from epileptic attacks. In this study, we present an automatic method that reduces the artifact from the raw signals, and then classifies the seizure and non-seizure epochs. At all stages, it is assumed that no information is available about the patient and this detection is made only based on the information of other patients. The data from this study were recorded in Temple Hospital and the recording conditions were not controlled, so... 

    Studying Time Perception in Musician and Non-musician Using Auditory Stimuli

    , M.Sc. Thesis Sharif University of Technology Niroomand, Niavash (Author) ; Hajipour, Sepideh (Supervisor)
    Abstract
    Time perception is a concept that describes how a person interprets the duration of an event. Depending on the circumstances, people may feel that time passes quickly or slowly. So far, the understanding, comparison, and estimation of the time interval have been described using a simple model, a pacemaker accumulator, that is powerful in explaining behavioral and biological data. Also, the role of the frequency band, Contingent Negative Variation (CNV), and Event-Related Potential (ERP) components have been investigated in the passage of time and the perception of time duration. Still, the stimuli used in these studies were not melodic. Predicting is one of the main behaviors of the brain.... 

    Evaluation Auditory Attention Using Eeg Signals when Performing Motion and Visual Tasks

    , M.Sc. Thesis Sharif University of Technology Bagheri, Sara (Author) ; Hajipour, Sepideh (Supervisor)
    Abstract
    Attention is one of the important aspects of brain cognitive activities, which has been widely discussed in psychology and neuroscience and is one of the main fields of research in the education field. The human sense of hearing is very complex, impactful and crucial in many processes such as learning. Human body always does several tasks and uses different senses simultaneously. For example, a student who listens to his/her teacher in the class, at the same time pays attention to the teacher, looks at a text or image, and sometimes writes a note.Using the electroencephalogram (EEG) signal for attention assessment and other cognitive activities is considered because of its facile recording,... 

    Emotion Recognition from EEG Signals using Tensor based Algorithms

    , M.Sc. Thesis Sharif University of Technology Einizadeh, Aref (Author) ; Hajipour, Sepideh (Supervisor)
    Abstract
    The brain electrical signal (EEG) has been widely used in clinical and academic research, due to its ease of recording, non-invasiveness and precision. One of the applications can be emotion recognition from the brain's electrical signal. Generally, two types of parameters (Valence and Arousal) are used to determine the type of emotion, which, in turn, indicate "positive or negative" and "level of extroversion or excitement" for a specific emotion. The significance of emotion is determined by the effects of this phenomenon on daily tasks, especially in cases where the person is confronted with activities that require careful attention and concentration.In the emotion recognition problem,... 

    Diagnosis of Depressive Disorder using Classification of Graphs Obtained from Electroencephalogram Signals

    , M.Sc. Thesis Sharif University of Technology Moradi, Amir (Author) ; Hajipour, Sepideh (Supervisor)
    Abstract
    Depression is a type of mental disorder that is characterized by the continuous occurrence of bad moods in the affected person. Studies by the World Health Organization (WHO) show that depression is the second disease that threatens human life, and eight hundred thousand people die due to suicide every year. In order to reduce the damage caused by depression, it is necessary to have an accurate method for diagnosing depression and its rapid treatment, in which electroencephalogram (EEG) signals are considered as one of the best methods for diagnosing depression. Until now, various researches have been conducted to diagnose depression using electroencephalogram signals, most of which were... 

    Attitude Control of a 3DOF Quadrotor Stand Using a Heuristic Nonlinear Controller

    , M.Sc. Thesis Sharif University of Technology Alizad Arabolye Bishe, Meysam (Author) ; Nobahari, Hadi (Supervisor)
    Abstract
    A new heuristic controller, called nonlinear model predictive control based on gravitational search algorithm, is proposed for nonlinear systems. Nonlinear model predictive control involves the solution at each sampling instant of a finite horizon optimal control problem subject to nonlinear system dynamics and constraints. The new controller formulates nonlinear model predictive control problem as a single stochastic dynamic optimization problem and uses a system of virtual masses to find the best control signal at each sampling instant. For this purpose, a cost function is defined to evaluate each point of the search space. This function minimizes simultaneously the tracking error, control... 

    Drop formation from a capillary tube: comparison of different bulk fluid on newtonian drops and formation of newtonian and non-newtonian drops in air using image processing

    , Article International Journal of Heat and Mass Transfer ; Volume 124 , 2018 , Pages 912-919 ; 00179310 (ISSN) Nazari, A ; Zadkazemi Derakhshi, A ; Nazari, A ; Firoozabadi, B ; Sharif University of Technology
    2018
    Abstract
    The formation of water drops as a Newtonian fluid and formation of a shear-thinning non-Newtonian fluid, Carboxyl Methyl Cellulose (CMC) from a capillary into different bulk fluids are experimentally investigated. A high speed camera is used to visualize the images of the drops and an image-processing code employed to determine the drop properties from each image. It was found that the properties of the water drops when they are drooped into the liquids bulk fluids such as toluene and n-hexane are almost the same while they differed substantially when they were drooped into the air bulk fluid. It is shown that during the formation of water drop in all three kinds of bulk fluids, the drop... 

    Effect of radial structure on the performance of lateral high-power GaAs photoconductive switch

    , Article IEEE International Conference on Electro Information Technology, 21 May 2015 through 23 May 2015 ; Volume 2015-June , 2015 , Pages 436-439 ; 21540357 (ISSN) ; 9781479988020 (ISBN) Hemmat, Z ; Moreno, E ; Rasouli, F ; Alizad, S. H ; Sharif University of Technology
    IEEE Computer Society  2015
    Abstract
    In this paper, the effect of radial structure on the performance of a linear-lateral GaAs high power photoconductive semiconductor switch (PCSS) is investigated. For this purpose a three-dimensional device modeling is used to model the optically initiated GaAs switch. In this simulation a p-type device with carbon as shallow acceptor is compensated by deep donor EL2 level as a trap level. The PCSS device is designed in a back-triggered, radially symmetric switch structure which extends the blocking voltage by reducing the peak electric field near the electrodes. Device modeling was performed and the effect of different trap concentrations on dark I-V characteristics has been investigated. In... 

    Decentralized Relative Position and Heading Estimation in Formation Flight Considering Geometric Constraints

    , Ph.D. Dissertation Sharif University of Technology Alizad Arabloue Bisheh, Meysam (Author) ; Nobahari, Hadi (Supervisor)
    Abstract
    This thesis addresses the problem of decentralized relative localization in multi-UAV systems operating in GNSS-denied environments. A novel algorithm is developed that leverages relative range and inertial measurements to jointly estimate relative positions, velocities, heading angles, and acceleration biases. By incorporating geometric constraints—such as the law of cosines and velocity relations—into the estimation process, the proposed approach significantly reduces bias errors and improves overall accuracy. Each group of three UAVs forms a triangular configuration, enabling members to exploit spatial relations and share local estimates. A master–regular structure is also considered,... 

    A multi-stage stochastic mixed-integer linear programming to design an integrated production-distribution network under stochastic demands

    , Article Industrial Engineering and Management Systems ; Volume 17, Issue 3 , 2018 , Pages 417-433 ; 15987248 (ISSN) Derakhshi, M ; Akhavan Niaki, S. T ; Akhavan Niaki, S. A ; Sharif University of Technology
    Korean Institute of Industrial Engineers  2018
    Abstract
    Supply chain management has gained much interest from researchers and practitioners in recent years. Proposing practical models that efficiently address different aspects of the supply chain is a difficult challenge. This research investigates an integrated production-distribution supply chain problem. The developed model incorporates parties with a specified number of processes to obtain raw materials from the suppliers in order to convert them to semi and final products. These products are then distributed through warehouses to end-distributors having uncertain demands. This uncertainty is captured as a dynamic stochastic data process during the planning horizon and is modeled into a... 

    EEG-based Emotion Recognition Using Graph Learning

    , M.Sc. Thesis Sharif University of Technology Talaie, Sharareh (Author) ; Hajipour Sardouie, Sepideh (Supervisor)
    Abstract
    The field of emotion recognition is a growing area with multiple interdisciplinary applications, and processing and analyzing electroencephalogram signals (EEG) is one of its standard methods. In most articles, emotional elicitation methods for EEG signal recording involve visual-auditory stimulation; however, the use of virtual reality methods for recording signals with more realistic information is suggested. Therefore, in the present study, the VREED dataset, whose emotional elicitation is virtual reality, has been used to classify positive and negative emotions. The best classification accuracy in the VREED dataset article is 73.77% ± 2.01, achieved by combining features of relative... 

    Detection of High Frequency Oscillations from Brain Electrical Signals Using Time Series and Trajectory Analysis

    , M.Sc. Thesis Sharif University of Technology Gharabaghi, Ali (Author) ; Hajipour Sardouie, Sepideh (Supervisor)
    Abstract
    The analysis of cerebral signals, encompassing both invasive and non-invasive electroencephalogram recordings, is extensively utilized in the exploration of neural systems and the examination of neurological disorders. Empirical research has indicated that under certain conditions, such as epileptic episodes, cerebral signals exhibit frequency components exceeding 80 Hz, which are designated as high frequency oscillations. Consequently, high frequency oscillations are recognized as a promising biomarker for epilepsy and the delineation of epileptic foci. The objective of this dissertation is to evaluate the existing methodologies for the detection of high frequency oscillations and to... 

    High Frequency Oscillation Detection in Brain Electrical Signals Using Tensor Decomposition

    , M.Sc. Thesis Sharif University of Technology Yousefi Mashhoor, Reza (Author) ; Hajipour, Sepideh (Supervisor)
    Abstract
    High-frequency oscillations (HFOs) in brain electrical signals are activities within the 80–500 Hz frequency range that are distinct from the baseline and include at least four oscillatory cycles. Research indicates that HFOs could serve as potential biomarkers for neurological disorders. Manual detection of HFOs is time-consuming and prone to human error, making automated HFO detection methods increasingly necessary. These automated methods typically rely on the signal's energy within the HFO frequency band. Tensor decompositions are mathematical models capable of extracting hidden information from multidimensional data. Due to the multidimensional nature of brain electrical signals, tensor... 

    Extraction of Event Related Potentials (ERP) from EEG Signals using Semi-blind Approaches

    , M.Sc. Thesis Sharif University of Technology Jalilpour Monesi, Mohammad (Author) ; Hajipour Sardouie, Sepideh (Supervisor)
    Abstract
    Nowadays, Electroencephalogram (EEG) is the most common method for brain activity measurement. Event Related Potentials (ERP) which are recorded through EEG, have many applications. Detecting ERP signals is an important task since their amplitudes are quite small compared to the background EEG. The usual way to address this problem is to repeat the process of EEG recording several times and use the average signal. Though averaging can be helpful, there is a need for more complicated filtering. Blind source separation methods are frequently used for ERP denoising. These methods don’t use prior information for extracting sources and their use is limited to 2D problems only. To address these... 

    Design and Implementation of a P300 Speller System by Using Auditory and Visual Paradigm

    , M.Sc. Thesis Sharif University of Technology Jalilpour, Shayan (Author) ; Hajipour Sardouie, Sepideh (Supervisor)
    Abstract
    The use of brain signals in controlling devices and communication with the external environment has been very much considered recently. The Brain-Computer Interface (BCI) systems enable people to easily handle most of their daily physical activity using the brain signal, without any need for movement. One of the most common BCI systems is P300 speller. In this type of BCI systems, the user can spell words without the need for typing with hands. In these systems, the electrical potential of the user's brain signals is distorted by visual, auditory, or tactile stimuli from his/her normal state. An essential principle in these systems is to exploit appropriate feature extraction methods which... 

    An Investigation of Resting-State Eeg Biomarkers Derived from Graph of Brain Connectivity for Diagnosis of Depressive Disorder

    , M.Sc. Thesis Sharif University of Technology Arabpour, Mohammad Reza (Author) ; Hajipour, Sepideh (Supervisor)
    Abstract
    Among the most costly diseases that affect a person's quality of life throughout his or her life, mental disorders (excluding sleep disorders) affect up to 25 percent of people in any community. One of the most common types of these disorders in Iran is depressive disorder, which according to official statistics, 13% of Iranians have some symptoms of it. Until now, the diagnosis of this disease has been traditionally done in clinics with interviews and questionnaires tests based on behavioral psychology and using symptom assessment. Therefore, there is a relatively low accuracy in the treatment process. Nowadays, with the help of functional brain imaging such as electroencephalogram (EEG)...