Sharif Digital Repository

According to statistics published by the World Health Organization, 9.6% of men and 18% of women over the age of 60 exhibit symptoms of osteoarthritis(OA). Cur- rently, there is no cure for OA, but there are medications that have shown promising results. Drug delivery methods to the cartilage include oral and injectable adminis- tration, neither of which deliver sufficient amounts of the drug to the cartilage unless administered in high doses, which can cause toxicity. High-Intensity Focused Ultra- sound (HIFU) can play a role in drug delivery to the cartilage by creating a pressure field. HIFU application to the body is non-invasive as it is applied externally. Ad- ditionally, HIFU can... 

nowadays Acoustic play an important role in the treatment of various diseases, especially cancer. in 2020 cancer has been the cause of death for more than 10 million patients. High intensity focused ultrasound is a non-invasive technique that used successfully to treat Malignant cancers like liver, pancreas and prostate. One of the major problems of using acoustic waves is the absorption of high frequency waves by the tissue before reaching the target area. in this study, a finite element model used to find the relation between frequency and acoustic pressure of transducer and focal region intensity. the results show, the maximum intensity in focal region linearly proportional to frequency... 

FE simulations have been widely used to investigate the response of the brain tissue in various circumstances. The accuracy of the material models critically affects the results of the numerical simulation. However, despite the numerous studies aiming for the material modeling of the brain, there is still divergence between the results reported in the literature. A part of this discrepancy is due to the inherent difference between samples. Nonetheless, another part of it is resulted from the differences between testing protocols used by researchers. In some protocols multiple mechanical tests are performed on each sample. Enough recovery time should be considered between consecutive test... 

Today digital imaging systems have been widely used due to their ease of use and proper costs, but still they suffer from low contrast and resolution. Because of technical limits and expensiveness of hardware, software techniques like super resolution have been used. By super resolution we mean increasing the density of an image’s pixels. Super resolution can be categorized as “single image super resolution” and “multi-image super resolution”. Single image super resolution is applied on a low quality image which has blur and/or noise of environment and imaging system and increases its quality and density to an acceptable level. In multi-image super resolution some auxiliary images captured... 

Micro electromechanical systems (MEMS) such as sensors and actuators are gaining more popularity in recent years. These systems have different application in automation, medicine and other industries. Mechanical structures are governed by electrical systems in MEMS devices and this is one of the challenges of MEMS studies. Usually these systems made by one deformable beam or plate over a fixed substrate. Due to applied voltage between substrate and deformable plate or beam, the deformable plate deflects toward the fixed substrate. The voltage at which the system becomes unstableis called pull-in voltage. Pull-in voltage is the most important characteristics of MEMS beyond which pull-in takes... 

In this thesis, the influence of nonideal boundary conditions on the vibration of a functionally graded beam excited by a moving oscillator on Pasternak-type viscoelastic foundation has been investigated. The beam has simply-supported boundary conditions and is assumed that the right-hand-side boundary conditions allows for small deflection, moment and axial force. The beam property gradient is assumed to be in the thickness direction and varies according to the power law distribution. The Hamilton's principle is utilized to obtain the governing equations of motion under the assumptions of Euler-Bernoulli beam theory. The equations of motion of the beam are solved using an... 

Due to special characteristics, nowadays functionally graded materials are of great interest of researchers. Continuous change of properties in these materials,decreases undesirable phenomena such as stresscon centration. On the other hand knowing vibration parameters of structures such as natural frequencies, to avoid damage, is important. So far, many researches have been devoted to vibration analysis of structures, such as beams.In this dissertation, free vibration analysis of FGM beams, are investigated, using RKPM, a meshlesh method. The system of equations of motion is derived using Lagrange’s method under the assumption of Euler-Bernoulli beam theory. Buckling analysis of FGM beams... 

The ossicular chain of the human middle ear has a key role in sound conduction since it transfers vibrations from the tympanic membrane to the cochlea, connecting the outer and the inner part of the hearing organ. This study reports firstly a description of the main anatomical features of the middle ear to introduce a detailed survey of its biomechanics,focused on model development, with a collection of geometric, inertial and mechanical/material parameters. The joint issues are particularly discussed from the perspective of developing a model of the middle ear both explanatory and predictive. Such a survey underlines the remarkable dispersion of ... 

After Alzheimer and brain attack, the most common neurological disorder is epilepsy, which often involves seizures. In two-thirds of patients with epilepsy, the seizures can be controlled by antiepileptic drugs, and about 8% of patients can use epilepsy surgery; but unfortunately there is no acceptable treatment for the other 25% of these patients. Therefore preventing from epilepsy losses is a very important topic.
The gold standard for the diagnosis of the epilepsy is EEG monitoring. In this method, electrodes are placed on the scalp. Electrodes are uncomfortable to wear, and cause invasion to the patient, hence long-term monitoring and home monitoring is not feasible. In some... 

The purpose of this project is the analysis of free and forced vibrations of sandwich panels under moving loads. In order to analyze the problem, sandwich panels are modeled as composite square plates. By using third order shear deformation theory, equations of motion are derived. Equations of motion with six different boundary conditions are solved utilizing generalized differential quadrature method. Natural frequencies are obtained for simple cases reported in the literature.In addition, a sandwich panel under moving load with simply supported boundary conditions is analyzed and time series response of the middle point is obtained. The time series response is also studied parametrically... 

One of the main problems in human health, both in advanced societies and in growing societies, is a variety of cancers, one of which is brain tumor. One of the non-invasive methods of treating tumors is the use of ultrasound.HIFU (High Intensity Focused Ultrasound) therapy method is known as one of the most advanced surgical techniques in tumor ablation therapy. HIFU are produced and concentrated by powerful transducers. The two main mechanisms in HIFU are mechanical and thermal mechanisms, and the effects of these two mechanisms appear as thermal effects and cavitation. The fundamental mechanism in the HIFU is to absorb ultrasonic waves and to convert them into heat.The purpose of this... 

The injection process on cell is a very accurate and sensitive operation. This method is used for several new invented approaches such as tracytoplasmic Cell Injection or drug delivery. Controlling the injection force in micro scale is one of the problems of mentioned operations. Current huge and expensive laboratorial devices are helping the operators to do injection operation with :nore success. In this study a simple and novel microelectromechanical (MEMS) mechanism for doing injection process automatically on the biological cells is proposed. In order to controlling this device properly, we should model and simulate the operation condition from initial position to final condition. This... 

The need to supply energy of low voltage electronic circuits such as sensors and wireless systems has attracted many researchers in recent years. As a solution to this problem, the energy needed for electronic devices can be obtained from the surrounding environment. An important part of energy harvesters are the systems that use vibrating energy of mechanical devices known as vibration power generators. Most linear vibration generators are systems that operate in resonance mode. As the frequency of the environment moves away from the natural frequency of the generator, the amount of converted energy decreases significantly. For this reason, some solutions are needed to solve this problem. ... 

In drilling oil well with respect to depth of several thousand meters, knowing the physical conditions of down-hole well such as temperature, pressure and stress have particular importance in prevention of possible injuries such as breaking the drill bit or increasing temperature. If these data can transfer from down-hole to bore-hole of the well, the operators can prevent from critical conditions such as intertangle of the drill-string. Currently, because of this lack of information, there are irreparable damages in oil industry annually. Based on researches, because of down-hole conditions of the well, these data can’t transfer with electromagnetic telemetry. Currently one of the data... 

Drilling in oil industry, is an expensive process in produce and extract oil from well. Any mistake in drilling may cause many drawbacks for industry owners. Phisic’s quantities information at downhole like tempreture, pressure and force on bit synchronously can inform user from torrid conditions and prevent undesired events by actions like evoke bit from downhole or change at rotation velocity in drilling and finally stop operations. With attention to a lot of problems in data transport from long distance more than one kilometer from downhole, scientists believe that one of the methods to do this process is converting data gathered at the bottom hole to acoustic waves and transmit them to... 

The important role of MEMS devices in optical systems has initiated the development of a new class of MEMS called Micro-Opto-Electro-Mechanical Systems (MOEMS), which mainly includes nano/micromirrors and torsional nano/microactuators. These devices have found variety of applications in optical switches, displays, micro scanning mirrors, optical cross-connects, interferometery, spectroscopy, aberration correction and biomedical imaging. In this project, the static and dynamic behavior of electrostatic nano/micromirrors under the effect of intermolecular surface forces and squeezed film damping are studied. The prior art published in the literature have mainly used pure torsion models. In a... 

New development in material fabrication resulted in functionally graded materials (FGM) with properties, can vary continuously based on the desired purpose. Vast applications of these materials attracted scientists to extend the researches in this area. One of the promising applications of these materials is in the optimized spherical and cylindrical pressure vessels. Optimization is usually based on the minimization of heat transfer and maximization of the strength of the vessel under pressure. In the present dissertation, spherical and cylindrical pressure vessels are designed and characteristics of the material distribution for certain pressure and temperature is developed. In this... 

In this research, a functionally graded microbeam bonded with piezoelectric layers is analyzed under electric force. Static and dynamic instability due to the electric actuation is studied because of its importance in micro electro mechanical systems, especially in micro switches. In order to prevent pull-in instability, two piezoelectric layers are used as sensor and actuator. A charge amplifier is used to supply input voltage of the actuator from the output of the sensor layer. Using Hamilton's principle and Euler-Bernoulli theory, equation of motion of the system is obtained. It is shown that the load type (distributed or concentrated) applied to the microbeam from the piezoelectric... 

Cylinders are one of the most applicable components in industry. According to the application of these elements, reinforcement and stiffening are the common ways to enhance mechanical properties of them. Nowadays, by advent of new materials such as functionally graded materials (FGMs), a novel method of improving these structures is discovered. By application of FGMs, many physical and mechanical characteristics of these structures can be modified. In this thesis, vibration analysis and frequency optimization of a stiffened cylinder made from FGMs are performed. FGM which is employed in this investigation is made from two different materials, to have better modal properties which cause in... 

Building weight reducing idea and implementation of Lightweight Structures were always attractive for structural engineering experts, scholars and researchers around the world and its proven effects on improving behavior and reducing the forces acting on the structure, has urged researchers to create new designs. Concrete slabs are of a significant portion of the overall weight of the structure. Nowadays, waffle slabs are a demand for structural designers, as a consequence of architectural design evolution and new building management concepts, in spite of its laborious numerical modeling. The objective of this work was to analyze the adequacy of a design method widely used in the modeling of...