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    Green composite synthesis based on aluminum fumarate metal-organic framework (MOF) for doxorubicin delivery: an in vitro study

    , Article Journal of Drug Delivery Science and Technology ; Volume 101 , 2024 ; 17732247 (ISSN) Abbariki, N ; Bagherzadeh, M ; Aghili, S ; Daneshgar, H ; Sharif University of Technology
    2024
    Abstract
    The development of an eco-friendly and cost-effective drug delivery system (DDS) remains a challenge in cancer treatment. This study suggests a novel, eco-friendly, and cost-effective method to synthesize aluminum fumarate (A520) MOF using tangerine peel extract (TPE) as a pH-sensitive coating agent on a reduced graphene oxide (rGO) substrate. The system also incorporates the 2,2′-bipyridine dimethyltin diisothiocyanate complex, (Sn(bpy), as an organotin complex) to enhance therapeutic efficacy while minimizing off-target effects. In vitro cellular and molecular cytotoxicity examinations were conducted using HEK-293 and MCF-7 cell lines to evaluate cytotoxicity after 24 and 72 h. The... 

    Dynamic mutual manufacturing and transportation routing service selection for cloud manufacturing with multi-period service-demand matching

    , Article PeerJ Computer Science ; Volume 7 , 2021 , Pages 1-30 ; 23765992 (ISSN) Sadeghi Aghili, S. A ; Valilai, O.F ; Haji, A ; Khalilzadeh, M ; Sharif University of Technology
    PeerJ Inc  2021
    Abstract
    Recently, manufacturing firms and logistics service providers have been encouraged to deploy the most recent features of Information Technology (IT) to prevail in the competitive circumstances of manufacturing industries. Industry 4.0 and Cloud manufacturing (CMfg), accompanied by a service-oriented architecture model, have been regarded as renowned approaches to enable and facilitate the transition of conventional manufacturing business models into more efficient and productive ones. Furthermore, there is an aptness among the manufacturing and logistics businesses as service providers to synergize and cut down the investment and operational costs via sharing logistics fleet and production... 

    Scaling inertia properties of a manipulator payload for 0-g emulation of spacecraft

    , Article International Journal of Robotics Research ; Volume 28, Issue 7 , 2009 , Pages 883-894 ; 02783649 (ISSN) Aghili, F ; Namvar, M ; Sharif University of Technology
    2009
    Abstract
    This paper presents a method to control a manipulator system grasping a rigid-body payload so that the motion of the combined system as a consequence of external applied forces is the same as any other free-floating rigid-body (with different inertial properties). This allows 0-g emulation of a scaled spacecraft prototype under the test in a 1-g laboratory environment. The controller consisting of motion feedback and force/moment feedback adjusts the motion of the test spacecraft so as to match that of the flight spacecraft, even if the latter has flexible appendages (such as solar panels) and the former is rigid. The stability of the overall system is analytically investigated, and the... 

    Design of Novel Drugs Based on Tyrosine and Phenylalanine Amino Acids to Inhibit Cyclin-Dependent Kinases 2 (CDK2) Proteins Modeled on Flavopiridol Drug

    , M.Sc. Thesis Sharif University of Technology Aghili, Farshad (Author) ; Fattahi, Alireza (Supervisor)
    Abstract
    Cyclin-dependent kinases 2 (CDK2) are one of the important proteins in cell cycle regulation and progression. In many human cancer cells, the activity of CDK2 kinases and their related subunits are deregulated, leading to tumor formation. Therefore, inhibition of this enzyme as an attractive therapeutic target can cause cancer cell death in glioblastoma and diffuse large B-cell lymphoma. Using new pharmaceutical structures based on sugar and amino acids is a new approach due to its greater efficacy and fewer side effects than old drugs. In this research, according to the structure of Flavopiridol as one of the CDK2 inhibitors, the active site of CDK2, and the structure of ATP molecule, 50... 

    Stability Analysis of High Rise Structures Using the IDA Method

    , M.Sc. Thesis Sharif University of Technology Aghili, Amir (Author) ; Khaloo, Alireza (Supervisor)
    Abstract
    The increased height of high-rise structures has made the effects of reduced stability a crucial factor in structural analysis and design. There are a variety of methods for analyzing the stability of high-rise structures. This thesis discusses nonlinear finite element method for analyzing the stability of a three-dimensional 50-storey concrete structure with a height of 150 meter using increment dynamic analysis (IDA). The IDA was first proposed by Bertero.v and it has been adopted in a variety of manners by researchers. In recent years, this method has been confirmed by EEMA. Moreover, FEMA350, FEMA351 and FEMA P695 guidelines have paid special attention to this method for determining... 

    Dynamic mutual manufacturing and transportation routing service selection for cloud manufacturing with multi-period service-demand matching

    , Article PeerJ Computer Science ; Volume 7 , 2021 , Pages 1-30 ; 23765992 (ISSN) Sadeghi Aghili, S. A ; Fatahi Valilai, O ; Haji, A ; Khalilzadeh, M ; Sharif University of Technology
    PeerJ Inc  2021
    Abstract
    Recently, manufacturing firms and logistics service providers have been encouraged to deploy the most recent features of Information Technology (IT) to prevail in the competitive circumstances of manufacturing industries. Industry 4.0 and Cloud manufacturing (CMfg), accompanied by a service-oriented architecture model, have been regarded as renowned approaches to enable and facilitate the transition of conventional manufacturing business models into more efficient and productive ones. Furthermore, there is an aptness among the manufacturing and logistics businesses as service providers to synergize and cut down the investment and operational costs via sharing logistics fleet and production... 

    Attitude control of satellites with delay in attitude measurement

    , Article 2013 IEEE International Conference on Robotics and Automation, ICRA 2013 ; 2013 , Pages 947-952 ; 10504729 (ISSN); 9781467356411 (ISBN) Bahrami, S ; Namvar, M ; Aghili, F ; Sharif University of Technology
    2013
    Abstract
    Time delay in attitude sensors is one of the performance limiting factors in controlling the satellite attitude. In this paper, we investigate attitude control of a fully actuated satellite in presence of constant and known delay in attitude measurement. The proposed controller consists of a matrix gain which is computed by solving a time varying matrix differential equation depending on the time delay. We assume that the moment-of-inertia matrix of the satellite is unknown. The controller guarantees asymptotic convergence of the satellite attitude and angular velocity to their desired values in presence of delay. Finally, a simulation example is presented that illustrates performance of the... 

    Design, Synthesis and Use of Transition Metal Oxide Spinels (Cobalt and Iron) as Catalysts in Organic Reactions

    , M.Sc. Thesis Sharif University of Technology Aghili, Sara (Author) ; Matloubi Moghadam, Firouz (Supervisor)
    Abstract
    Bread scraps with transition metals oxides spinels have been utilized to synthesize¬ magnetic nanocatalyst. The heterogeneous catalyst was characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), Brunauer-Emmett-Teller (BET), thermogravimetric analysis (TGA) and transmission electron microscopy (TEM). The reaction was performed for tandem Knoevenagel-Micheal reaction in the presence of synthesized nanocatalyst as a heterogeneous, environmentally benign, cost-effective catalyst with high catalytic activity using EtOH as a green solvent. The magnetic nanocatalyst was applied to synthesize tetraketones and pyranopyrazoles... 

    Distributed Publisher-Subscriber Pattern for Content-Based Routing in Software Defined Networks

    , M.Sc. Thesis Sharif University of Technology Aghili, Shahrooz (Author) ; Hemmat Yar, Ali Mohammad Afshin (Supervisor)
    Abstract
    Content-based routing, as provided by publisher/subscriber systems,has evolved as a key paradigm for interactions between loosely coupled application components (content publishers and subscribers). Content-based routing aims to increase the efficiency of forwarding by utilizing the diversity of information exchanged between application components. Using content-based forwarding rules (also called content filters) installed on content-based routers (also termed brokers), bandwidth-efficiency is increased by only forwarding content to the subset of subscribers who are actually interested in the published content. Many middle-ware implementations for content-based publish/subscribe have been... 

    Hubert Dreyfus on the Impossibility of Artificial Intelligence: Consequences and Implications

    , M.Sc. Thesis Sharif University of Technology Aghili Dehkordi, Bamdad (Author) ; Sefidkhosh, Maysam (Supervisor) ; Taqavi, Mostafa ($item.subfieldsMap.e)
    Abstract
    Hubert Dreyfus other than being a prominent philosopher is amongst early critics of classical artificial intelligence project which was initialized during 1955-1960. Challenging the rationalist presuppositions of this paradigm, he foresaw various situations where mechanical artificial intelligence based upon modeling the world through symbolic representation and mimicking reason by formalized rules would fail to deliver even remotely similar outputs in digital computers as in human though process and problem solving ability.Twenty years later it became obvious for AI researchers that obstacles like frame problem or lack of common sense would follow their projects no matter what computing... 

    Dynamic control of spontaneous emission using magnetized InSb higher-order-mode antennas

    , Article JPhys Photonics ; Volume 6, Issue 3 , 2024 ; 25157647 (ISSN) Aghili, S ; Alaee, R ; Ahmadnejad, A ; Mobini, E ; Mohammadpour, M ; Rockstuhl, C ; Dolgaleva, K ; Sharif University of Technology
    2024
    Abstract
    We exploit InSb’s magnetic-induced optical properties to design THz sub-wavelength antennas that actively tune the radiative decay rates of dipole emitters at their proximity. The proposed designs include a spherical InSb antenna and a cylindrical Si-InSb hybrid antenna demonstrating distinct behaviors. The former dramatically enhances both radiative and non-radiative decay rates in the epsilon-near-zero region due to the dominant contribution of the Zeeman-splitting electric octupole mode. The latter realizes significant radiative decay rate enhancement via magnetic octupole mode, mitigating the quenching process and accelerating the photon production rate. A deep-learning-based... 

    The relationship between an EFL teacher's gender and students' willingness to communicate

    , Article International Journal of Communication and Linguistic Studies ; Volume 10, Issue 4 , 2013 , Pages 17-29 ; 23277882 (ISSN) Khosravizadeh, P ; Pakzadian, S. S
    Common Ground Publishing  2013
    Abstract
    Learning a foreign language encompasses a process of trial and error that can lead to the progression of the learner's interlanguage, meaning that the learners make use of their language knowledge that receives feedback and brings about progress through diagnosis of the problems and being corrected by the teacher. Therefore, there exists a need to analyze the underlying reasons causing the students to remain taciturn with a low willingness to communicate (WTC) during a language class. There has been much work done investigating the role of the learner's stable personal characteristics (traits) along with their situational changes at a specific time (states) that influence the student's... 

    Design and development of a miniaturized roto-translational motion platform for microaerial vehicle identification

    , Article IEEE Aerospace and Electronic Systems Magazine ; Volume 39, Issue 12 , 2024 , Pages 24-35 ; 08858985 (ISSN) Abdollahi, M. R ; Pourtakdoust, S. H ; Mousavi, S. M. S
    IEEE  2024
    Abstract
    Accurate system identification (SI) is essential for flight controller design of unmanned aerial vehicles and microaerial vehicles (MAVs). SI can be performed either in frequency or time domain using flight test data. As flight testing is often costly and may even lead to catastrophic events before some flight stability analysis is at hand, a low-cost 5 degree-of-freedom free motion platform (FMP) is designed and used for initial identification of MAVs via wind tunnel testing. A typical MAV is constructed as a test case and equipped with inertial sensors for testing and validation purposes. The proposed FMP allows for both rotational as well as translational motions that in turn provide for... 

    An automated simple algorithm for realistic pore network extraction from micro-tomography images

    , Article Journal of Petroleum Science and Engineering ; Vol. 123, issue , 2014 , pp. 164-171 ; ISSN: 09204105 Rabbani, A ; Jamshidi, S ; Salehi, S
    2014
    Abstract
    Using 3-D scanned data to analyze and extract pore network plays a vital role in investigation of porous media's characteristics. In this paper, a new simple method is developed to detect pores and throats for analyzing the connectivity and permeability of the network. This automated method utilizes some of the common and well-known image processing functions which are widely accessible by researchers and this has led to an easy algorithm implementation. In this method, after polishing and quality control of images, using city-block distance function and watershed segmentation algorithm, pores and throats are detected and 3-D network is produced. This method can also be applied on 2-D images... 

    Discrimination of heart arrhythmias using novel features in heart rate phase space

    , Article Computing in Cardiology ; Volume 40 , Sept , 2013 , Pages 1035-1038 ; 23258861 (ISSN); 9781479908844 (ISBN) Moharreri, S ; Rezaei, S ; Salavatian, S
    2013
    Abstract
    In this paper, we try to recognize and distinguish different groups of arrhythmia using novel features which have been obtained from the heart rate's phase space in recent years. For this purpose, we used Triangular Phase Space Mapping (TPSM) and Parabolic Phase Space Mapping (PPSM). For recognition, we used three groups of 15 subjects using the Physionet database (Arrhythmia, Congestive Heart Failure (CHF), and Atrial Fibrillation (AF)) with Normal Sinus Rhythm (NSR). The obtained features discriminate arrhythmia from NSR by p

    An intelligent hybrid classification algorithm integrating fuzzy rule-based extraction and harmony search optimization: Medical diagnosis applications

    , Article Knowledge-Based Systems ; Volume 220 , 2021 ; 09507051 (ISSN) Mousavi, S. M ; Abdullah, S ; Akhavan Niaki, S. T ; Banihashemi, S ; Sharif University of Technology
    Elsevier B.V  2021
    Abstract
    Uncertainty is a critical factor in medical datasets needed to be overcome for increasing diagnosis efficiency. This paper proposes an intelligent classification algorithm comprising a fuzzy rule-based approach, a harmony search (HS) algorithm, and a heuristic algorithm to classify medical datasets intelligently. Two fuzzy approaches, as well as orthogonal and triangular fuzzy sets, are first utilized to define the attributes of data. Then, an HS algorithm is integrated with a heuristic to generate fuzzy rules to select the best rules in the fuzzy rule-based systems. Moreover, to improve the performance of the proposed classification approach, a three-phase parameter tuning approach is... 

    Performance evaluation of shared hosting security methods

    , Article Proc. of the 11th IEEE Int. Conference on Trust, Security and Privacy in Computing and Communications, TrustCom-2012 - 11th IEEE Int. Conference on Ubiquitous Computing and Communications ; 2012 , Pages 1310-1315 ; 9780769547459 (ISBN) Mirheidari, S. A ; Arshad, S ; Khoshkdahan, S ; Sharif University of Technology
    2012
    Abstract
    Shared hosting is a kind of web hosting in which multiple websites reside on one webserver. It is cost-effective and makes the administration easier for websites' owners. However, shared hosting has some performance and security issues. In default shared hosting configuration, all websites' scripts are executed under the webserver's user account regardless of their owners. Therefore, a website is able to access other websites' resources. This security problem arises from lack of proper isolation between different websites hosted on the same webserver. In this survey, we have examined different methods for handling mentioned security issue. Also we evaluated the performance of mentioned... 

    The behaviour of an artificially cemented sandy gravel

    , Article Geotechnical and Geological Engineering ; Volume 23, Issue 5 , 2005 , Pages 537-560 ; 09603182 (ISSN) Haeri, S. M ; Hosseini, S. M ; Toll, D. G ; Yasrebi, S. S ; Sharif University of Technology
    2005
    Abstract
    The major section of the city of Tehran, Iran has been developed on cemented coarse-grained alluvium. This deposit consists of gravely sand to sandy gravel with some cobbles and is dominantly cemented by carbonaceous materials. In order to understand the mechanical behaviour of this soil, a series of undrained triaxial compression tests and unconfined compression tests were performed on uncemented and artificially cemented samples. Portland cement type I was used as the cementation agent for preparing artificially cemented samples. Uncemented samples and lightly cemented samples (1.5% cement) tested at high confining pressure showed contractive behaviour accompanied with positive excess pore... 

    An imperialist competitive algorithm approach for multi-objective optimization of direct coupling photovoltaic-electrolyzer systems

    , Article International Journal of Hydrogen Energy ; Vol. 39, Issue 33 , 11 November , 2014 , pp. 18743-18757 ; ISSN: 03603199 Maroufmashat, A ; Sayedin, F ; Khavas, S. S
    2014
    Abstract
    In the context of sustainable clean hydrogen production pathways, photovoltaic-electrolyzer systems are one of the most promising alternatives for acquiring hydrogen from renewable energy sources. In fact, determining the optimal set of design and operating variables are always a key issue while coupling directly renewable electricity sources to PEM electrolyzers. Few previous studies have attempted to find the optimal size and operational condition of directly coupled photovoltaic-electrolyzer (PV/El) systems in order to maximize the hydrogen production or to minimize energy transfer loss between photovoltaic devices and the electrolyzer. Nevertheless an easy and efficient approach still... 

    Kalman filter based packet loss replacement in presence of additive noise

    , Article 2012 25th IEEE Canadian Conference on Electrical and Computer Engineering: Vision for a Greener Future, CCECE 2012 ; 2012 ; 9781467314336 (ISBN) Miralavi, S. R ; Ghorshi, S ; Tahaei, A
    2012
    Abstract
    A major problem in real-time packet-based communication systems, is misrouted or delayed packets which results in degraded perceived voice quality. If packets are not available on time, the packets are considered as lost. The easiest solution in a network terminal receiver is to replace silence for the duration of lost speech segments. In a high quality communication system, to avoid degradation in speech quality due to packet loss, a suitable method or algorithm is needed to replace the missing segments of speech. In this paper, we introduce an adaptive filter for replacement of lost speech segment. In this method Kalman filter as a state-space based method will be used to predict the...